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Contribution Towards Genetic Discoveries Related to Male Pattern Baldness BY 23andMe

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23andMe, a leading personal genetics company has contributed to the finding of six novel genetic associations for early onset male pattern baldness (androgenetic alopecia) in a genome-wide association study now published online in the journal iPLoS Genetics/i. They made the contribution using data from their unique online research platform. "The 23andMe Research Platform is a robust source of new genetic discoveries. Nearly 90 percent of our more than 150,000 customers participate in our ...

Trichotillomania: Hair Loss From Pulling Your Hair

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Trichotillomania is an impulse control disorder in which the patient suffers from a severe urge to pull hair from the scalp, eyelids, eyebrows and pubic area. Frequently pulling outhair could lead to noticeable hair loss and bald patches, that further aggravate distress and social or functional impairment. This is a rare and chronic disorder and treatment poses a challenge to doctors. Trichotillomania occurs in infants as early as 18 months, but the peak of the onset is during the teenage....

Hair Loss Prevention Drug Linked to Risk of Sexual Problems

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A new study published in the Journal of Sexual Medicine warns that hair loss prevention drug Propecia could increase the risk of long term sexual problems in almost all of those who use the drug. The study was conducted by researchers at George Washington University who observed 54 men under 40 years of age who were using Propecia. The researchers found that over 96 percent of those who used the drug experienced sexual problems, including erectile dysfunction, for more than a year after they stopped taking the drug....

Onions and Hair Loss

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In the era where doctors and scientists have developed vaccines and medicines for major disease around the world, the permanent and efficient cure for hair loss is still not found. Thick,b /blustrous and healthy hair isb/bcharacteristic of youth and a crowning glory for men and women. Hair fall causes stress and depression. Change in lifestyle, pollutants in the environment, and certain health issues can cause excessive hair fall. Surprisingly, onion is an ingredient in ...

Special Cap Helps Prevent Chemotherapy Hair Loss

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A new cooling cap designed by scientists helps chemotherapy patients prevent hair loss during therapy. The DigniCap system has been adopted by Imperial College Healthcare NHS Trust for use in its chemotherapy day units at Charing Cross and Hammersmith Hospitals, the Daily express reported. Patients wear a special cap, which cools their scalp, and also prevents hair loss. The system continuously keeps a check on the temperature to ensure consistent application of the cooling treatment, ...

Researchers Say Timing of Cancer Radiation Therapy May Minimize Hair Loss

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Researchers suspect that hair loss in humans from toxic cancer radiotherapy and chemotherapy might be minimized if these treatments are given late in the day. This suspicion comes after the discovery that mouse hair has a circadian clock - a 24-hour cycle of growth followed by restorative repair. The study, which appears in the early online edition of the iProceedings of the National Academy of Sciences/i (PNAS), found that mice lost 85 percent of their hair if they received radiation therapy ...

Prince Harry Facing Hair Loss

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Prince Harry is losing his hair just like elder brother, reveal experts. It has been predicted that the royal will shed much of his hair by the age of 50, the Daily Star reported. Surgeons have also urged the Prince to have emergency hair treatment to avoid losing his heart-throb status. Dr Nadeem Uddin Khan told the publication that Harry should party as much as he wants because it will all catch up with him. Khan, who runs Harley Street Hair Clinic - which did a hair transplant ...

US Researchers Invent New Hair Restoration Method to Beat Hair Loss

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Researchers in the US claim to have invented a hair restoration method that can generate new human hair growth and solve the problem of baldness. Researchers at the Columbia University Medical Centre (CUMC) have devised a hair restoration method that can generate new human hair growth, rather than simply redistributing hair from one part of the scalp to another. According to the study, published Monday in the online edition of the Proceedings of the National Academy of Sciences (PNAS), the ...

Gravity Could be the Reason for Male Pattern Baldness

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While researchers continue to search for the cause and cure to male pattern baldness, a new study suggests that gravity could be the reason for the condition that affects almost all men as they enter middle age. Researchers led by Dr Emin Tuncay Ustuner from Ankara, Turkey, said that gravity exerts a force of downward pull on the scalp skin which could be responsible for male pattern baldness, also known as androgenic alopecia (AGA). Dr Ustuner's theory attempts to solve the puzzle of high levels ...

Kim Kardashian Suffers from Hair Loss

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33-year-old reality TV star Kim Kardashian is suffering from tracton alopecia (hair loss), reveal sources. According to a UK website, Tatiana Karelina, leading hair extension expert analyzed photos of the 33-year-old reality TV star and claimed that she needs to stop using weaves immediately, News.com.au reported. She said that birth and rapid weight loss are both factors that have triggered her thinning hair and the pulling and weight of hair extensions often cause severe migraines and Traction Alopecia....

Simple Tips to Stop Hair Loss Menopause

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Menopause hair loss is a common problem that affects about half of women during menopause. Simple lifestyle changes to a woman's daily routine are necessary to take control of hair loss. Hair is made from a type of protein called keratin, which is also present in the skin and nails. Most people have about 100,000 hairs, which remain on the head for several years at a time. Each hair may grow for two to six years before going into a resting phase. Eventually, the hairs fall out, and most people lose between 50 and 100 hairs every day....

New Lease of Life for Alopecia Patients

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Nothing lasts forever, not even your hair! Your hair length, style and color actually frames your face and ultimately your personality. It is normal to lose some strands of hair every day, due to the end of life cycle of a hair strand. However, the cause for concern arises when you see an abnormal or persistent loss of a href="http:www.medindia.net/slideshow/top-ten-foods-for-healthy-hair.asp" target="_blank" class="vcontentshlink"hair/a, which could be quite distressing and causes lot ...

Serious Doubts, Questions Persist About a Popular Drug to Treat Hair Loss

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Researchers claim that a review of 34 clinical trials on a popular drug to treat hair loss in men found that none of the studies adequately reported on sexual side effects. The findings raise serious questions about whether the drug -- known as finasteride and marketed as Propecia and Proscar, among other names -- is safe, said the report by scientists at Northwestern University, published in the iJournal of the American Medical Association/i (JAMA) Dermatology on Wednesday. The drug, ...

Drug Used to Treat Hair Loss in Men Affects Sexual function; Side Effects Not Reported

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Male hair loss is often treated with a drug called finasteride. It blocks 5alpha-reductase in the scalp and male reproductive organs, inhibiting the conversion of the male hormone testosterone to its more potent form, 5alpha-dihydrotestosterone (5alpha- DHT). Men who take finasteride experience a 70% reduction in the amount of 5alpha-DHT in their blood. The Northwestern University study has revealed that not one of the 34 published clinical trial reports of finasteride's sexual dysfunction side ...

India Prevents UK Company From Patenting Traditional Hair Loss Formula

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An attempt made by UK-based Dermaceutical Laboratory, Pangaea Laboratories Limited, to take patent on a medicinal composition containing turmeric, pine bark and green tea for treating hair loss was prevented by India. Traditional Knowledge Digital Library (TKDL), a Unit of Council of Scientific and Industrial Research, located the patent application filed at European Patent office by M/S Pangaea Laboratories Limited and filed pre-grant opposition along with prior-art evidences from TKDL, proving ...

Get Rid of Hair Loss Once and for All! FDA-Approved Drugs Restore Hair Growth

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Suffering with hair loss? Then here is a good news for you. In experiments with mouse and human hair follicles, researchers have found that certain existing drugs promote rapid and robust hair growth when directly applied to the skin.The study raises the possibility that drugs that inhibit the Janus kinase (JAK) family of enzymes could be used to restore hair growth in multiple forms of hair loss such as that induced by male pattern baldness."What we have found is promising, though we have not yet ...

New Promising Option Restores Hair Growth in People With Hair Loss

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Hair fall has become quite common among several people. Home remedies do not always work when trying to boost hair growth. Inhibiting a family of enzymes inside hair follicles that are suspended in a resting state restores hair growth, revealed a study by researchers at Columbia University Medical Center. In experiments with mouse and human hair follicles, Angela M. Christiano and colleagues found that drugs that inhibit the Janus kinase (JAK) family of enzymes promote rapid and robust hair growth when directly applied to the skin....

Take It Easy on Your Hairstyle to Prevent Hair Loss

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Styling your soft locks a certain way can make you lose hair. Traction alopecia or gradual hair loss is due to damage from repeated or prolonged tension on the roots. Following hairstyles marked by stretching, such as pulling the hair back tightly through tight ponytails, braids and dreadlocks, and extensions can cause gradual hair loss. A review of 19 studies found a "strong association" between traction alopecia and scalp-pulling hairstyles, which are common among African Americans. ...

Drug for Alopecia Areata Could Bid Good Bye for Hair Loss and Baldness

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bHighlights/b ul class="group-list punch-points"liAlopecia areata leads to hair loss in patches or in large clumps that could even lead to total hair loss./liliIt is an auto-immune condition that has no known cure./liliStudy utilizes ruxolitinib, earlier used for bone marrow malignancies and tofacitinib, earlier used for arthritis. /lili95% hair regrowth witnessed among alopecia areata after the use of these drugs for 3 months. ...

Ways to Combat Hair Loss

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Nourish your hair with a warm oil massage, explore the goodness of butea gum tree and more to have thick and strong tresses, suggests an expert. Ashok, Research Scientist at The Himalaya Drug Company, suggests how: A warm oil massage can be the best remedy to provide your hair with the required amount of nourishment. The massage can not only relieve you of your pent-up stress but also accelerate blood circulation on the scalp, thus reducing the possibility of hair loss. Hair dryers ...

Effect of Scalp Cooling Treatment on Hair Loss in Women Undergoing Chemotherapy

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bHighlights/bul class="group-list punch-points" liOne of the significant side-effects of chemotherapy is hair loss also known as alopecia./li liScientists investigated whether use of a scalp cooling system lowers the amount of hair loss among women receiving chemotherapy regimens for breast cancer. /li liScalp cooling uses a device which is refrigerated and placed on the patient before the chemotherapy session and is not removed or changed until the treatment is completed. /li/ul a href="http:www....

Hair Loss -- Defective Skin Immune Cell Link Unearthed

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bHighlights:/b ul class="group-list"liAlopecia is a common disease leading to hair loss from the scalp, face and eyebrows, whose cause remains unknown./liliCurrent study has identified the role of regulatory T-cells (Tregs) in promoting hair growth by triggering stem cells in the hair follicles of the skin./li/ul Regulatory T-cells in skin are critical in inducing stem cells within hair follicles to regenerate and cause hair growth, according to scientists from UC San Francisco....

Women Pay More Than Men for Common Hair Loss Medication Minoxidil

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Minoxidil foam is a hair loss remedy that has been most commonly used. Women would pay an average of 40% more than men, finds a new analysis from the research team at the Perelman School of Medicine at the University of Pennsylvania. The difference in prices may appear despite the men's and women's version of the products that could be branded and marketed differently. This could contain the same drug strength and inactive ingredients. The study findings are published in the journal iJAMA Dermatology....

Rare Skin Disease and Male Pattern Baldness Share Genetic Link

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An inherited disorder of skin, hair follicles, nails, sweat glands, and teeth called hypohidrotic ectodermal dysplasia (HED) shares a mechanism that may also be disrupted in male pattern baldness. About one in 5,000 to 10,000 people are thought to have HED, although this may be an underestimate of its actual prevalence as this condition is not always diagnosed correctly. HED is most frequently caused by mutations in the EDA, EDAR, EDARRAD and WNT10A genes. In addition to its association with ...

Black Women With Common Form of Hair Loss at Risk for Fibroids

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A research term, after studying medical records of hundreds of thousands of African-American women, have found evidence that women with a common form of hair loss have an increased chance of developing uterine leiomyomas, or fibroids. In a report on the research, published in iJAMA Dermatology/i, the researchers call on physicians who treat women with central centrifugal cicatricial alopecia (CCCA) to make patients aware that they may be at increased risk for fibroids and should be screened ...

New Study Sheds Light on Conditions from Alopecia to Cancer

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Key finding about Wnt signaling associated with developmental defects and a myriad of diseases ranging from alopecia to colorectal cancer has been discovered by University of Dundee and the Francis Crick Institute researchers. The research, jointly led by Dundee's Dr Gopal Sapkota and Professor Sir Jim Smith of the Crick, examined the role of a protein called PAWS1 in the Wnt signalling pathway, which is of fundamental importance in shaping developing embryos and controlling cell fate in adults....

Hair Loss Drug may Help Remodel Stiff Arteries

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Minoxidil, drug used to stimulate hair growth has shown to increase elastin deposition in mature human tissue, revealed study published in American Journal of Physiology--Heart and Circulatory Physiology. Arteries in young, healthy humans and other mammals stretch easily because they contain a protein called elastin. Elastin is produced only during development, however, and is slowly lost with aging. In older people, arteries stiffen as elastin is lost. Stiff arteries contribute to development ...

Simple Tips to Prevent Hair Loss During Weight Loss

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Is sudden weight loss causing hair loss? Lack of enough proteins, iron and other dietary supplements in the human body can cause hair loss. Inadequacy of such nutrients makes our hair thirsty and deprived from their desired nourishment which eventually makes them fall. Arvind Poswal, hair expert at Dr. A's Clinic and Mandeep Singh, fitness expert at Step-On Fitness Center have rolled out some significant tips to reduce weight without causing any damage to your hair: Intake of ample proteins ...

Immunosuppressants Side Effect May Benefit People With Hair Loss

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bHighlights:/bul class="group-list punch-points"liMen and women who suffer from baldness can be benefited by a drug (WAY-316606) designed to treat osteoporosis./liliDr. Hawkshaw and team developed a new strategy to promote hair re-growth particularly in cases of androgenetic alopecia./liliIsolated human hair follicles showed a positive effect when tested in organ cultures, and the result could one day make a dream come true./li/ul Hair loss ...

Wrinkled Skin and Hair Loss Reversed in Mouse Model

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In a mouse model scientists have reversed aging-associated skin wrinkles and hair loss. Keshav Singh, Ph.D., and colleagues have done just that, in a mouse model developed at the University of Alabama at Birmingham. When a mutation leading to mitochondrial dysfunction is induced, the mouse develops wrinkled skin and extensive, visible hair loss in a matter of weeks. When the mitochondrial function is restored by turning off the gene responsible for mitochondrial dysfunction, the mouse returns ...

New Drug for Hair Loss and Skin Damage Caused by Fatty Diet

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Hair loss, hair whitening, and skin inflammation caused by fatty diet may be reversed with a newly identified drug called D-PDMP, which can be taken either as a capsule or as a liquid. The new drug is identified by a research team at Johns Hopkins Medicine. The investigators say the compound halts the production of certain fats called glycosphingolipids, or GSLs, that are major components of skin and other cell membranes. Current research shows that mice fed a diet high in fat and cholesterol ...

Gene That Causes Hair Loss Could Help Treat Cancer

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Gene that causes hair loss can help improve cancer immunotherapy suggests a new mouse study. The findings of the study are published in the journal iCell Systems/i. "While immunotherapies have shown great promise in cancer, most patients do not benefit from these treatments because their tumors can evade the immune system," said study leader Angela M. Christiano, Ph.D., the Richard and Mildred Rhodebeck Professor of Dermatology and Genetics and Development at Columbia University Vagelos College of Physicians and Surgeons....

Novel Gene Responsible for Rare Form of Hair Loss Identified

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New study discovers a new gene that is responsible for the rare form of hair loss, called hypotrichosis simplex. The findings of the study are published in the iAmerican Journal of Human Genetics/i. Changes in the LSS gene lead to impairment of an important enzyme that has a crucial function in cholesterol metabolism. In infancy, fine hair tends to sprout sparsely. With increasing age, hair loss progresses. Ultimately, only a few hairs are left on the head and body. Hypotrichosis simplex is a rare form of hair loss (alopecia)....

Society Committed to Fighting Hair Loss Gains Huge Popularity

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A society committed to fighting hair loss has caught huge attention in Malaysia. The Malaysian Society for Hair Sciences, which was registered in 2002, educates people on hair loss disorders and the various medical treatment options available to them. The 400-member club, including dermatologists, general practitioners and scientists, with an interest in the science of hair, organizes hair forums, once every two years, apart from regular public and professional educational events....

Genes Causing Hair Loss Identified

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Eight genes causing alopecia areata, an autoimmune skin disease that, in turn, could lead to total or partial loss of hair have been identified by American researchers. For the research, America's National Alopecia Areata Foundation Scientific Advisory Council member Dr. Angela Christiano led a team of investigators from Columbia University Medical Center. Part of the significance of this recent finding is that many of the genes found to be associated with alopecia areata are ...

DigniCap may Help Prevent Hair Loss in Cancer Patients Undergoing Chemo

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DigniCap, a new frozen gel-filled cap may help prevent hair loss in cancer patients undergoing chemotherapy. According to Msnbc.com, four patients in the U.S. are trying out the DigniCap-a hat that contains a cooling gel and fits tightly on the head. During the treatment, the gel chills the hair follicles, thus restricting the amount of chemotherapy that reaches them. Heather Millar of San Francisco, one of the patients trying out the experimental treatment, managed to retain most of ...

Adverse Effects of Hair Loss Drug- Loss of Libido, ED in Men

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Researchers from Boston University School of Medicine (BUSM), in collaboration with colleagues at Lahey Clinic and from Denmark and Germany, have found that 5a-reductase inhibitors (5a-RIs), while improving urinary symptoms in patients with benign prostatic hyperplasia (BPH) and possible hair loss prevention, produces significant adverse effects in some individuals including loss of libido, erectile dysfunction (ED), ejaculatory dysfunction and potential depression. These findings, which currently ...

Potential Hair Loss Treatment Accidentally Emerges from Mice Study

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US researchers exploring how stress affects the gut stumbled upon a potent chemical that caused mice to regrow hair by blocking a stress-related hormone, a study revealed on Wednesday. While the process has not yet been tested in humans, it grew more hair in mice than minoxidil, the ingredient in Rogaine, a popular treatment for baldness, said the study in the online journal PLoS One. "This could open new venues to treat hair loss in humans through the modulation of the stress hormone receptors, ...

Scalp Cooling Cap May Prevent Hair Loss in Cancer Patients

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Scientists have now developed a scalp cooling cap which may help prevent hair loss in breast cancer patients undergoing chemotherapy treatment. This will be part of the first significant study of the medical device in the United States. The FDA has given approval for an investigational device exemption (IDE) feasibility study to be conducted at both Wake Forest Baptist and University of California, San Francisco (UCSF). A total of 20 patients with stage one breast cancer will be involved - 10 at Wake Forest Baptist and 10 at UCSF....

Men Report Sexual Side Effects After Use of Common Hair Loss Drugs

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Men who take the hair loss drug finasteride, commonly known as Propecia and Proscar, report an on-going reduction in sex drive, and in some cases, prolonged periods of erectile dysfunction even after they stop using the medications. "The study by The George Washington University School of Medicine and Health Sciences, looked at the reported types and duration of persistent sexual side effects in otherwise healthy men who took finasteride for male pattern hair loss," said Dr. Michael Irwig, Assistant Professor of Medicine....

New Breakthrough in Cancer Hair Loss Treatment Discovered

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A new way to protect the hair follicle from chemotherapy in an effort to prevent hair loss as a result of cancer treatments has been discovered by scientists. The study from the laboratory of Professor Ralf Paus of the Centre for Dermatology Research describes how damage in the hair follicle caused by taxanes, cancer drugs which can cause permanent hair loss, can be prevented. To do this, scientists have exploited the properties of a newer class of drugs called CDK4/6 inhibitors, which ...

Hair Loss Linked To Severity of COVID-19 in Men

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Novel biomarker, that identifies male COVID-19 patients who are at higher risk for ICU admission, is discovered by researchers at i Lugano, /i as presented at i EADV's 2021 Spring Symposium. /i The findings suggest that b men with genetic characteristics (phenotypes) sensitive to the male sex hormone androgen, are more likely to experience severe COVID-19 disease. /b As the disproportionate number of men who were hospitalized with COVID-19 presented with androgenetic alopecia ...

Hair Loss Adds To The List Of Post-COVID Complications

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bHighlights:/bul class="group-list punch-points"li Massive influx of cases experiencing post-COVID hair loss has been reported at a Delhi hospital/liliThis sudden onset of hair loss is termed telogen effluvium/lili Experts believe that nutritional deficiency, stress reactions, and inflammation in the patients are the main reasons for this post-COVID hair loss/liliWith proper treatment, the condition might improve within 2-3 months /li/ul Significant acceleration in ...

Natural Supplements Help Reverse Hair Loss During Menopause

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bHighlights :/bul class="group-list punch-points"liFemale pattern hair loss in middle-aged women is multifactorial/liliBut, interventions to treat the hair loss address only the hormone issue/liliMany women find it difficult to incorporate into daily haircare routine/liliTo overcome this, a novel nutraceutical supplement is developed to provide a multi-targeted approach/li/ul Hair loss is a complex and multi-factorial problem that is commonly seen in middle-aged women ...

New Pill Causes Hair Regrowth in 40% Men With Alopecia

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Concert Pharmaceuticals has developed the new twice-a-daily pill and says that starting trial results have been promising. Four in 10 patients suffering from alopecia areata were able to regrow nearly a full head of hair within six months. Unfortunately, the scientist behind the drug says it can't be used by the millions of men worldwide who lose their hair as the age. The drug targets a more specific cause called alopecia areata. This is when the body attacks its own hair follicles. h2Regrowth ...

New Discovery Goes Beyond Hair Loss Treatment to Cure Baldness, Speed Up Wound Healing

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Chemical controlling life and death in hair follicles may help treat baldness and also speedup wound healing, suggests a new study. A single chemical is the key to controlling when hair follicle cells divide, and when they die. This discovery could not only btreat baldness/b, but ultimately bspeed wound healing/b because follicles are a source of stem cells. Most cells in the human body have a specific form and function determined during embryonic development that does not change. For ...

Hair Loss Problems: Do Women Suffer Receding Hairline Like Men

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Receding hairline (hair loss) is no more only a man's problem, say experts. Losing your hair might cause you to lose confidence and cause emotional stress. There are several reasons why you can be dealing with a receding hairline; history of the family, stress, inadequate nutrition, too much perspiration, illness, age, treatments or medications, and changes in hormones. Some of the reasons are difficult to deal with but mostly a lot are under our control and can be reversed to a lot of extents....

Hair Loss and Belly Fat: Decoding the Unexpected Connection for a Healthy Mane

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bHighlights:/b ul class="group-list" li There is an indirect link between belly fat and hair loss. Hormones like insulin-like growth factor (IGF-1) play a role in this /li li Unhealthy lifestyle choices, including excess belly fat, can contribute to hair loss /li li Exercise, balanced nutrition, and stress management can be effective strategies to support hair health and prevent hair loss /li/ul medlinkBelly fat/medlink, also known as pot belly, has become a common ...

Telogen Effluvium: Understanding Hair Loss as a Sequela of COVID-19

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bHighlights:/b ul class="group-list" li Telogen effluvium (TE) is observed as a manifestation of COVID-19, leading to diffuse hair loss in infected individuals /li li The study found that a significant percentage of COVID-19-recovered patients experienced hair loss, with varying timelines of onset /li li Recognizing COVID-19 as a potential cause of hair loss can aid in patient education and understanding the transient nature of the condition /li/ul The medlinkCOVID-19 ...

Genetic Insights Into Androgenetic Alopecia

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Scientists in /medlink Bonn pinpoint uncommon genetic mutations linked to male-pattern hair loss. From receding hairlines to the iconic horseshoe baldness pattern, prior studies on androgenetic alopecia have mainly focused on common genetic factors (!--ref1--). Human geneticists from the University Hospital of Bonn (UKB) and the Transdisciplinary Research Unit "Life (and) Health" of the University of Bonn have now performed a systematic investigation of the extent to which rare genetic variants may also contribute to this disorder....





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